ea0037gp.20.02 | Pituitary – Hypopituitarism | ECE2015
van Bunderen Christa C
, Meijer Rick I
, Lips Paul
, Kramer Mark H
, Serne Erik H
, Drent Madeleine L
Objective: Epidemiological evidence for a link between serum IGF1 concentration and cardiovascular disease in the general population and in patients with GH deficiency or hypersecretion has been demonstrated. However, the underlying mechanisms remain unresolved. We investigated associations between IGF1 levels within the reference range and different measures of cardiovascular function and risk factors in substituted GH deficient adults within a randomized clinical trial.<...